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Adenomatoid mesothelioma is a specific subset ofepithelioid mesothelioma. It is sometimes known as glandular or microglandular mesothelioma. This subtype is one of the more common secondary patterns of epithelial malignant mesothelioma.
Any type of mesothelioma can have an adenomatoid growth pattern. Pleural, peritoneal or pericardial mesotheliomas may all feature an adenomatoid differentiation.
Adenomatoid mesothelioma can mimic several other types of tumors, including benign adenomatoid tumors and pleural metastases of adenocarcinoma. To correctly diagnose a patient with adenomatoid mesothelioma, doctors will need to evaluate the patient's clinical presentation as well as the unique histological features of the tumor.
The adenomatoid subtype of epithelial mesothelioma is not the same thing as an adenomatoid mesothelial lesion. Adenomatoid lesions can grow in mesothelial cells, but these tumors have a different cellular makeup than malignant mesothelioma tumors. Adenomatoid lesions typically develop in genital organs, but they can also arise in the pleura, mesentery or omentum. Thesebenign tumors are very small and lack significant cellular abnormalities.
Adenomatoid mesothelioma cells can be either flat or cube-shaped. In adenomatoid mesothelioma, the cells line small, gland-like structures.
As with other types of epithelioid mesothelioma, adenomatoid mesothelioma grows in a uniform pattern. Some adenomatoid tumors grow into microcystic structures. These patterns can have a lace-like appearance.
Adenomatoid growth patterns may coexist with other growth patterns in epithelial mesothelioma tumors. However, the adenomatoid pattern is often the predominant pattern.
Malignant adenomatoid mesotheliomas are often diagnosed differently than benign adenomatoid lesions. The benign growths often develop in the genital tract (in both males and females), and they are often diagnosed incidentally during a pelvic surgery. A handful of these tumors have also been detected in the pleura during a debulking surgery for other lung masses.
However, when doctors diagnose a patient with malignant mesothelioma of the adenomatoid variety, thediagnostic process is the same as it is for any other type of malignant mesothelioma. Patients typically present with chest pain, shortness of breath and coughing. The oncologist then runs several imaging scans and biopsies that lead to diagnosis.
In rare cases, benign adenomatoid tumors have also appeared in the following locations:
Because adenomatoid mesotheliomas look very similar to other adenomatoid lesions, doctors need to look for specific markers to differentiate between the two conditions. When diagnosing adenomatoid mesothelioma, doctors primarily look forpleural thickening and pleural nodules. These two characteristics are typically absent in cases of benign adenomatoid tumors. To diagnose adenomatoid lesions, doctors look for fibrous stroma (soft tissues) and bland, will well-defined cell borders.
While benign adenomatoid tumors are typically easy to remove through surgery, malignant adenomatoid mesothelioma is more difficult to treat. The therapeutic options include surgery, chemotherapy and radiation therapy. However, one study showed that the mean survival of seven patients who received treatment for adenomatoid mesothelioma was 10 months from the time of diagnosis.
Weisserferdt, A, et al. Malignant mesothelioma with prominent adenomatoid features: A clinicopathologic and immunohistochemical study of 10 cases. Annals of Diagnostic Pathology. (February 2011). Retrieved fromhttp://www.annalspathology.com/article/S1092-9134%2810%2900154-1/references
Malignant Mesothelioma has been linked to workplace asbestos exposure.
Malignant Mesothelioma is rare form of cancer that affects lining of the lungs, abdomen, heart, and major organs in the body. Mesothelioma is a disease in which malignant cancer cells are found in the sac lining the chest (pleura) or the abdomen (peritoneum). There are about 3,000 new malignant Mesothelioma cases diagnosed each year in the U. S. If you are experiencing any Mesothelioma symptoms you should contact a doctor immediately.
If you or a family member has been diagnosed with malignant Mesothelioma you are going to have a lot of questions about living with Mesothelioma and what legal options you have against asbestos manufacturers and asbestos companies for your asbestos exposure. Mesothelioma is a seriously deadly disease. According to the American Cancer Society with the average survival time for people with Mesothelioma is 4-18 months. CallTOLL FREE 800.291.0963 right now to talk with a live Mesothelioma Counselor that can answer many of your questions and give you the peace of mind that you need.
If you have a family member that has died from Mesothelioma cancer you should immediately consult with an experienced Mesothelioma diagnosis lawyer about what compensation may be available to you from asbestos trust funds that total more than 30 billion dollars. It isVERY IMPORTANT that you file your Mesothelioma claim within your states Statute of Limitations. We have seen many families lose their right to file a lawsuit because their Statute of Limitations had expired while they were grieving. We know it is a tough time to grieve the loss of a loved one, but please do not let your Statute of Limitations expire for filing your Mesothelioma lawsuit. In most states the Statute of Limitations is 2-3 years. Some states have 6 year Statute of Limitations.
Mesothelioma has a long latency period of 10-50 years. Many Veterans, Shipyard Workers, Construction Workers, Power Plant Workers, Mill Workers, Steel Workers, Railroad Workers, Pipefitters, Insulators, Electricians, Carpenters, Welders, Auto Mechanics, Veterans, Factory Workers, and laborers are living in the early stages of a variety of asbestos related diseases. Many Mesothelioma lawyers will not accept asbestosis, asbestos lung cancer, asbestosis, pleural plaques, pleural thickening, colon cancer and esophageal cancer cases.
If you or a family member has been diagnosed with Mesothelioma or an asbestos related disease, we can help you start a Mesothelioma lawsuit against asbestos companies responsible for your injuries. Our experienced nationwide Mesothelioma lawyers will come to you.Call our Mesothelioma Toll Free Helpline at 800.291.0963 and get help today!
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